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. 2017 Sep 11;12:6735–6746. doi: 10.2147/IJN.S140992

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© 2017 Zhao et al. This work is published and licensed by Dove Medical Press Limited

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Characteristics of lipid–polymer NPs.

Notes: (A) Size distribution of FA-PPLNPs/Mtx based on DLS; (B) FA-PPLNPs/Mtx nanosuspension; (C) SEM images of FA-PPLNPs/Mtx; (D) hydrodynamic diameters of various NPs. Values are mean ± SD (n=3).

Abbreviations: NPs, nanoparticles; FA-PPLNPs/Mtx, methotrexate-loaded folic acid–polyethylene glycol–poly(lactic-co-glycolic acid)–poly(cyclohexane-1,4-diylacetone dimethylene ketal)–lipid NPs; DLS, dynamic light scattering; SEM, scanning electron microscopy; PNPs, poly(lactic-co-glycolic acid)-NPs; PLNPs, poly(lactic-co-glycolic acid)–lipid NPs.