Table 4, appendix.
Characteristics of patients who have TCS Modifier in INTERMACS by INTERMACS Profile
| Entire Cohort | Profile 1 | Profile 2 | Profile 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| TCS Yes (n=2207) | TCS No (n=6225) | TCS Yes (n=982) | TCS No (n=555) | TCS Yes (n=895) | TCS No (n=2991) | TCS Yes (n=330) | TCS No (n=2679) | p-value | |
|
| |||||||||
| Age | |||||||||
| Group, yrs† | <0.001 | ||||||||
| <50 | 665 (30%) | 1615 (26%) | 324 (33%) | 194 (35%) | 257 (28%) | 781 (26%) | 84 (25%) | 640 (24%) | |
| 50–69 | 1349 (61%) | 3703 (59%) | 590 (48%) | 314 (56%) | 556 (62%) | 1810 (60%) | 203 (62%) | 1579 (59%) | |
| ≥70 | 193 (8.8%) | 907 (15%) | 68 (7%) | 47 (9%) | 82 (10%) | 400 (14%) | 43 (13%) | 460 (17%) | |
|
| |||||||||
| Male | 1725 (78%) | 4870 (78%) | 751 (77%) | 413 (74%) | 706 (79%) | 2340 (78%) | 268 (81%) | 2117 (79%) | 0.84 |
|
| |||||||||
| BMI, kg/m2 | 28.3 ± 0.1 | 28.5 ± 0.1 | 28.7 ± 0.2 | 27.8 ± 0.3 | 27.9 ± 0.2 | 28.5 ± 0.1 | 28.5 ± 0.4 | 28.7 ± 0.1 | 0.26 |
|
| |||||||||
| ISCM | 1076 (49%) | 2740 (44%) | 543 (55%) | 244 (44%) | 379 (42%) | 1291 (43%) | 154 (47%) | 1206 (45%) | <0.001 |
|
| |||||||||
| BTT | 596 (27%) | 1676 (27%) | 219 (22%) | 145 (26%) | 276 (31%) | 897 (30%) | 91 (28%) | 634 (24%) | <0.001 |
|
| |||||||||
| Prior Sternotomy | 1479 (67%) | 4188 (67%) | 120 (12%) | 48 (8.6%) | 74 (8.3%) | 246 (8.2%) | 37 (11%) | 243 (9.1%) | 0.006 |
|
| |||||||||
| Creatinine, mg/dL | 1.4 ± 0.04 | 1.4 ± 0.1 | 1.5 ± 0.03 | 1.6 ± 0.04 | 1.4 ± 0.03 | 1.5 ± 0.01 | 1.4 ± 0.04 | 1.4 ± 0.01 | 0.14 |
|
| |||||||||
| Albumin, g/dL† | 3.1 ± 0.02 | 3.5 ± 0.01 | 2.9 ± 0.03 | 3.2 ± 0.03 | 3.2 ± 0.02 | 3.4 ± 0.01 | 3.3 ± 0.05 | 3.5 ± 0.02 | <0.001 |
|
| |||||||||
| INR† | 1.4 ± 0.01 | 1.3 ± 0.01 | 1.4 ± 0.02 | 1.4 ± 0.02 | 1.4 ± 0.01 | 1.3 ± 0.01 | 1.3 ± 0.02 | 1.3 ± 0.01 | <0.001 |
|
| |||||||||
| Cardiac Arrest*,† | 289 (13%) | 157 (2.5%) | 214 (22%) | 72 (13%) | 57 (6.4%) | 64 (2.1%) | 18 (5.5%) | 21 (0.8%) | <0.001 |
|
| |||||||||
| Ventilator† Support | 353 (16%) | 203 (3.3%) | 298 (30%) | 115 (21%) | 43 (4.8%) | 70 (2.3%) | 12 (3.6%) | 18 (0.7%) | <0.001 |
|
| |||||||||
| Dialysis† | 83 (3.8%) | 66 (1.1%) | 53 (5.4%) | 25 (4.5%) | 28 (3.1%) | 28 (0.9%) | 2 (0.6%) | 13 (0.5%) | <0.001 |
|
| |||||||||
| Inotrope† | 1950 (88%) | 5788 (93%) | 855 (87%) | 486 (88%) | 828 (93%) | 2789 (93%) | 267 (81%) | 2513 (94%) | <0.001 |
|
| |||||||||
| Vasopressor † | 371 (17%) | 250 (4.0%) | 259 (26%) | 94 (17%) | 96 (11%) | 104 (4%) | 16 (5%) | 52 (2%) | <0.001 |
|
| |||||||||
| IABP† | 1390 (63%) | 919 (15%) | 567 (58%) | 236 (43%) | 628 (70%) | 457 (15%) | 195 (59%) | 226 (8.4%) | <0.001 |
|
| |||||||||
| Temp-LVAD | 129 (5.8%) | --- | 37 (3.8%) | -- | 39 (4.4%) | -- | 53 (19%) | -- | -- |
|
| |||||||||
| Temp-RVAD | 15 (0.7%) | --- | 11 (1.1%) | -- | 3 (0.3%) | -- | 1 (0.3%) | -- | -- |
|
| |||||||||
| ECMO | 248 (11%) | --- | 215 (22%) | -- | 27 (3%) | -- | 6 (2%) | -- | -- |
n(%) or mean ± standard error mean shown n(%) shown.
*
denotes cardiac arrest during index admission prior to VAD.
†
p <0.05 for comparison between TCS yes and no in whole cohort.
Abbreviations: INR = International normalized ratio, BMI= body mass index, BTT=bridge to transplant, ECMO=extracorporeal membrane oxygenation within 48 hours of operation, IABP= intra-aortic balloon pump within 48 hours of operation, ISCM=ischemic cardiomyopathy,