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. 2016 Feb 3;5:401–407. doi: 10.1016/j.bbrep.2016.02.002

Fig. 4.

Fig. 4.

Soluble ST2 suppressed IL-33-mediated production of IL-5 and IL-13 in lung ILC2. (A) Naïve lung ILC2 were pretreated as in Fig. 2 (C) and then stimulated with IL-33 for 24 h. Intracellular IL-4, IL-5, and IL-13 were detected by flow cytometry. The numbers in each quadrant indicate the percentage of cells. Results are representative of three independent experiments. (B) Naïve lung ILC2 were pretreated as in Fig. 2 (C) and then stimulated with IL-33 for 96 h. Culture supernatants were collected, and then applied to ELISA for measurement of IL-5 and IL-13. The data are shown as the means±SEM (**, p<0.01, IL-33 or In-ST2-V5+IL-33 versus other groups).