Table 3. Association between obesity measures and recurrent venous thromboembolism.
| Measure of obesity | No of events/patients | IR (95% CI) | Adjusted SHR* (95% CI) |
|---|---|---|---|
| Body mass index, kg/m2 | |||
| Categorized | |||
| <25 | 44/342 | 6.7 (5.0 to 9.0) | Reference |
| 25 to <30 | 43/402 | 4.6 (3.4 to 6.3) | 0.79 (0.52–1.22) |
| ≥30 | 35/242 | 6.3 (4.5 to 8.8) | 1.12 (0.71–1.78) |
| Continuous, per unit | 122/986 | 5.7 (4.8 to 6.8) | 1.02 (0.98–1.06) |
| Waist circumference, cm | |||
| Categorized | |||
| <80 (w) / <94 (m) | 15/109 | 6.8 (4.1 to 11.3) | Reference |
| 80 to <88 (w) / 94 to <102 (m) | 18/157 | 5.6 (3.5 to 8.9) | 0.89 (0.45–1.78) |
| ≥88 (w) / ≥102 (m) | 76/624 | 5.4 (4.3 to 6.8) | 0.98 (0.55–1.72) |
| Continuous, per unit | 109/890 | 5.6 (4.7 to 6.8) | 1.01 (0.99–1.02) |
Abbreviations; IR = incidence rate; CI = confidence interval, SHR = sub-hazard ratio.
*Adjusted for age, sex, heart failure, inflammatory bowel disease, presence of hemiparesis, hemiplegia, or paraplegia, prior varicose vein surgery (as a proxy for varicose veins), type of the index VTE (unprovoked, provoked, or cancer-related), prior history of VTE, localization of VTE (PE ±DVT vs. DVT alone), family history of DVT or PE, and periods of anticoagulation as a time-varying covariate