Table 3. Top ranking alignments of informative library peptides to the T. cruzi proteome.
T. cruzi protein | Total Score | Target 20mer | # peptide hits | TrTrypDB Gene ID | |
---|---|---|---|---|---|
1 | *Mucin: TcMucII | 3473 | TRAPSRLREVDGSLGSSAWV | 63 | TcCLB.509753.300 |
2 | Uncharacterized protein | 3329 | RRLSYRLRKREDGESYESYL | 59 | TcCLB.510575.140 |
3 | Uncharacterized protein | 3181 | VPVLRVVDAEADERERNGAG | 56 | TCSYLVIO_001012 |
4 | *Calmodulin | 3096 | TEVDVREALRVLDADGDGFL | 57 | TcCLB.510121.50 |
5 | Uncharacterized protein | 3091 | SYRQQRYVDALRFALEEDHE | 56 | TcCLB.508269.50 |
6 | *Mucin: TcMucII | 3032 | RAPSRLREFDGSLSSSAWVC | 56 | TcCLB.506741.110 |
7 | Uncharacterized protein | 3007 | KLRQLDFVEDVLRKHPDKVE | 52 | TcCLB.507011.170 |
8 | *Dispersed gene family protein 1 (DGF-1) | 2983 | HRGGLEALLRDGEDGDEDAQ | 58 | TcCLB.509735.84 |
9 | Uncharacterized protein | 2973 | LPAQDSVVVRRLVDGQAPLR | 51 | TcCLB.506267.48 |
10 | Vacuolar protein sorting-associated protein (Vps26) | 2966 | ERSPGLLGRLLRKVDGCDVR | 52 | TCSYLVIO_008174 |
* The families in which these proteins are members have been previously identified as antigenic