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. 2017 Sep 15;12(9):e0183662. doi: 10.1371/journal.pone.0183662

Fig 1. Docetaxel-induced TNF-α levels in media of breast and ovarian tumor cells are dose- and time-dependent.

Fig 1

A) and B) Effects of treatment time on TNF-α release by 2.5 nM docetaxel from MCF-7 and A2780 cells; C) and D) Effects of docetaxel concentration on TNF-α release in breast and ovarian cancer cell lines over 72 hours. The data represents the mean of three replicates (+ SEM). The significance of differences in secreted TNF-α levels between treated and untreated (NT) cells was assessed using a two-tailed T-test;*** p<0.0001.