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. 2017 Sep 15;12(9):e0185019. doi: 10.1371/journal.pone.0185019

Table 2. Associations between sickness behaviour, mAQLQ, self-rated health and inflammatory cytokines reported in quartiles with quartile 1 as reference.

Women
Sickness1
mAQLQ2 SRH3 Men
Sickness1
mAQLQ2 SRH3
IL-5
quartile 3 -0.02 -0.16 0.00 -0.07 -0.08 0.02
quartile 4 -0.27 -0.07 0.08 -0.22 0.15 -0.11
IL-6
quartile 2 0.01 -0.02 0.22 -0.36* 0.07 -0.24
quartile 3 -0.03 0.13 0.21 -0.54*** -0.05 -0.37*
quartile 4 0.04 -0.33 0.25 -0.26 -0.28 -0.18

*p<0.05;

**p<0.01;

***p<0.001

1Composite variable of rating of energy, sleep, memory, fitness and appetite where higher scores denote more pronounced sickness behaviour

2Higher scores denotes better asthma-related quality of life

3Higher scores on self-rated health denote worse self-rated health

The cytokines values were z-transformed to facilitate interpretation of b-coefficients. All models were adjusted for age and BMI and included all available data points.