Table 1.

Top 30 compound hits which upregulate the expression of NFAT-luciferase reporter.

	Compounds	Targets	Mean values of relative luciferase activity (log10)
1	Kenpaullone	Cdks/GSK3β	1.012
2	CK2 Inhibitor 2	Casein kinase II	0.858
3	Roscovitine	Cdks	0.789
4	Phenamil methanesulfonate	Amiloride-sensitive Na+channels	0.765
5	3-Deazaadenosine	S-adenosyl homocysteine hydrolase	0.716
6	SU 4312	VEGF receptor-2	0.602
7	SB-366791	TRPV1 receptor	0.580
8	PD 98059	MEK	0.539
9	SIB 1757	mGluR5	0.521
10	6-Methyl-2-(phenylethynyl)pyridine hydrochloride	mGluR5	0.476
11	Apigenin	Casein kinase II	0.454
12	SIB 1893	mGluR5	0.440
13	1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride	Ser/Thr kinase inhibitor	0.427
14	Tyrphostin AG 1296	PDGF receptor kinase	0.413
15	H-8 dihydrochloride	PKA	0.396
16	BF-170 hydrochloride	Tau	0.354
17	9-Cyclopentyladenine	Adenylyl cyclase	0.343
18	1,4-PBIT dihydrobromide	iNOS	0.333
19	N6-Cyclohexyladenosine	Adenosine A1 receptor	0.332
20	Lansoprazole	Proton pump	0.322
21	Phenserine	Acetylcholinesterase	0.312
22	D-ribofuranosylbenzimidazole	RNA polII	0.308
23	1-Phenyl-3-(2-thiazolyl)-2-thiourea	Dopamine β-hydroxylase	0.307
24	Riluzole	Sodium channels	0.302
25	Ciproxifan hydrochloride	H3 receptor	0.301
26	AMG 9810	TRPV1 receptor	0.281
27	Clorgyline hydrochloride	Monoamine oxidase	0.274
28	Olomoucine	Cdks	0.268
29	Chloro-IB-MECA	Adenosine A3 receptor	0.264
30	N-Methyl-beta-carboline-3-carboxamide	Benzodiazepine receptor	0.255