FL3 and FL37 increase protein expression of known flavagline targets PHB and PHB2 in IECs. A, Polarized Caco2-BBE cells were treated with increasing concentrations of FL3 or FL37 for 2 hours. Representative Western blots are shown for PHB, PHB2, and β-actin (loading control). B, Caco2-BBE cells were treated with 10 nM FL3 or FL37 for increasing time. Representative Western blots are shown for PHB, PHB2, phospho-p38-MAPK, total p38-MAPK, and β-tubulin (loading control).