Table 2.
Comparison of Her-2 D-FISH assay per the 2013 and 2007 ASCO/CAP guidelines in 255 consecutive cases of BCa
| ASCO 2013 | Equivocal versus Others | Positive versus Others | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Negative | Equivocal | Positive | Total | Mcnemar | Kappa | Mcnemar | Kappa | ||
| ASCO 2007 | Negative | 166(65.1) | 31(12.2) | 7(2.7) | 204(80.0) | P<0.001 | P=0.132 | P=0.002 | P<0.001 |
| Equivocal | 1(0.4) | 2(0.8) | 3(1.2) | 6(2.4) | |||||
| Positive | 0(0.0) | 0(0.0) | 45(17.6) | 45(17.6) | |||||
| Total | 167(65.5) | 33(12.9) | 55(21.6) | 255(100.0) | |||||
Her-2 D-FISH: Her-2 dual-probe fluorescent in situ hybridization
BCa: Breast Cancer