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. Author manuscript; available in PMC: 2018 Sep 11.
Published in final edited form as: Cancer Cell. 2017 Sep 11;32(3):295–309.e12. doi: 10.1016/j.ccell.2017.08.003

Figure 4. Restricted normal tissue expression of GPC2 and alternative GPC2 transcript expression.

Figure 4

(A) Summary of GPC2 membrane staining H-scores from a pediatric normal tissue array (total n = 36 unique normal tissues, n of each organ system or individual tissue indicated on X-axis). Summary of GPC2 membrane H-scores from neuroblastoma primary tumors/PDXs shown for comparison.

(B) RNA transcript specific analysis of GPC2 expression in primary neuroblastomas and the low-level GPC2 expressing normal tissues skin and esophagus (n = 126 high-risk neuroblastomas, TARGET; n = 201 esophagus samples and 684 skin samples, GTEx).

Data in A represent means ± SEM. Box plots in B extend from the first to the third-quartile, the horizontal line is the median, “+” represents the mean and the error bars represent the 1.5 interquartile range from the first-and third-quartile.

CV, cardiovascular; GI, gastrointestinal; GU, genitourinary.

See also Figure S4; Table S2.