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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Mucosal Immunol. 2017 Feb 22;10(3):580–588. doi: 10.1038/mi.2017.4

Figure 2.

Figure 2

Results of a genome-wide association study of EoE. Data from 736 subjects with EoE and 9,246 controls over 1,468,075 common genetic variants are graphed in a Manhattan plot. The −log10 P-value of each probability is shown as a function of genomic position on the autosomes. Genome-wide significance (red dashed line; P = 5 × 10−8) and suggestive significance (solid blue line; P = 1 × 10−7) are indicated. CAPN14, Calpain-14; HSF2BP, Heat Shock Transcription Factor 2 Binding Protein; LRRC32, Leucine Rich Repeat Containing 32; MIR4675, microRNA 4675; TSLP, Thymic stromal lymphopoietin; XKR6, XK Related 6. (From ref. 5.)