Table 1.

Lower and upper limits of quantitation (LLOQ and ULOQ) and extraction recovery. For the LLOQ, the accuracy had to be within 80–120% with less than 20% imprecision and the signal had to be at least five-fold higher than that of a blank sample. Recovery was determined in samples collected from 6 different individuals at 3 different levels for each analyte. Mean recoveries ± standard deviation (SD) are shown.

	Plasma				Urine
	LLOQ	ULOQ	% Recovery		LLOQ	ULOQ	% Recovery
	ng/mL	ng/mL	mean	SD	ng/mL	ng/mL	mean	SD
11OH-THC	1.56	400	103	3.6	1.56	400	97	5.1
CBN	1.56	400	73	3.4	1.56	400	96	4.4
CBG	0.78	400	86	1.4	0.78	400	96	1.8
THC	0.39	400	74	1.1	0.78	400	95	3.6
THCV	0.78	400	93	3.3	0.78	400	98	4.7
THC-COOH	0.39	400	73	3.1	1.56	400	100	2.1
THCV-COOH	0.78	400	88	3.4	3.13	400	101	4.5
CBD	0.39	400	87	3.6	0.78	400	98	4.7
CBC	0.78	400	60	1.3	0.78	400	94	3.0
CBDV	0.78	400	98	2.4	0.78	400	99	3.3
THC-C-gluc	3.91	2000	71	6.0	3.91	2000	99	3.2