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Study design. Subjects are treated for induced hemorrhage with 3:1 resuscitation formula (BR), decision-assist infusion (DA) and autonomous closed-loop (CL) infusion at separate time points (min. 4 weeks apart). Endpoint measurements are taken at various time points before and after hemorrhage. A-Line: arterial line. PIV: peripheral intravenous line. ICG: Indocyanide Green. GA: general anesthesia. Hb: Hemoglobin. Hct: Hematocrit.
