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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Mar 29;1863(10 Pt A):2414–2435. doi: 10.1016/j.bbadis.2017.03.020

Figure 2.

Figure 2

First reported melanocortin small molecule ligands, along with the hypothesized Ac-His-DPhe-Arg-Trp-NH2 melanocortin pharmacophore. The C-terminus of JB1n was reported as a mixture of an amide and carboxylic acid.