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. Author manuscript; available in PMC: 2018 Sep 15.
Published in final edited form as: Clin Cancer Res. 2017 May 23;23(18):5648–5656. doi: 10.1158/1078-0432.CCR-17-0291

Figure 1. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the assay.

Figure 1

With a requirement of >1 unique sequence reads (denoted by non-identical genome alignment coordinates), the sensitivity and specificity of the assay were 95% and >99.99%, respectively, for known variants at a variant allele frequency of 0.25%.