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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Prog Retin Eye Res. 2017 Mar 20;60:201–218. doi: 10.1016/j.preteyeres.2017.03.002

Figure 4.

Figure 4

Immunofluorescence confocal microscopy of a WT mouse given IVit vehicle (n=4) shows linear FH (red) staining (i) and PTX3 (green) staining (ii) in inner BrM (white arrowheads). (iii) Merged image of (i) and (ii) shows FH and PTX3 (yellow) staining overlap. WT mouse given 5 μg 4-HNE IVit (n=4) has diffuse staining in the RPE for FH (red) (iv) and PTX3 (green) (v). (vi) Merged image of (iv) and (v) shows FH and PTX3 (yellow) staining overlap. IgG isotype control for FH (vii) and PTX3 (viii). Reprinted with permission from Journal of Pathology.