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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2017 Jun;16(6):991–1001. doi: 10.1158/1535-7163.MCT-16-0876

Figure 1. Signaling pathways in cells with FLT3-ITD and mechanisms of action of drugs studied in combination with FLT3 inhibitors.

Figure 1

The figure shows different mechanisms involved in FLT3 inhibitor resistance, and drugs that can potentially prevent these processes when used in combination with FLT3 inhibitors.