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. 2017 Sep 12;8:215. doi: 10.3389/fendo.2017.00215

Table 2.

TSH values and LT4 dosage according to age.

18–29 (n: 188) 30–39 (n: 320) 40–49 (n: 455) 50–59 (n: 478) 60–69 (n: 248) 70–79 (n: 54) 80–89 (n: 12) P
TSH (mIU/mL) 5.5 ± 2.8 5.2 ± 3.5 5.1 ± 3 3.9 ± 0.4 3.03 ± 2 6.2 ± 2.1 4.8 ± 5.2 0.04
Duration of treatment (yrs) 5 ± 3.7 4.6 ± 4 5.7 ± 4 6.2 ± 5.6 7.3 ± 6 8.2 ± 5.2 13.7 ± 9 0.04
Daily dose (µg/day) 95.4 ± 49 95.7 ± 45 104 ± 56 91.3 ± 43 87.9 ± 39 94.9 ± 42 73.8 ± 35 0.001
Daily LT4 dosage (µg/kg) 1.44 ± 0.8 1.51 ± 0.6 1.34 ± 0.6 1.72 ± 0.3 1.59 ± 0.2 1.24 ± 0.5 1.04 ± 0.4 0.001

Yrs, years; LT4, levothyroxine.