Figure 2.

¹H MRI (T2W axial slice) and ¹H magnetic resonance spectroscopy chemical shift imaging (CSI) (echo time 135 ms, TR 2,200 ms, 3 averages, 4:41 min acquisition time, 200 ms Hanning filter) of healthy control (A), and patient with acute severe traumatic brain injury after craniectomy (B) acquired with a 12 channel ¹H volume coil on a Siemens 3 T scanner, data analysis performed with Siemens Syngo software. Panel (A) demonstrates the position of the selected voxel (blue square, ^†), represented in panel (C), within the CSI grid (hidden). (C) ¹H spectrum of 10 mm × 10 mm × 15 mm voxel ^† from healthy volunteer (A). (D) ¹H spectrum of 8 mm × 8 mm × 15 mm blue square voxel ^‡ of patient (B), within the CSI grid (hidden). Metabolite peaks are annotated in panels (C,D): Cr, creatine; Cho, choline; NAA, N-acetylaspartate, chemical shift on the x-axis in parts per million, signal intensity on y-axis using arbitrary units. Unpublished images by Tonny V. Veenith, courtesy of the Wolfson Brain Imaging Centre, Cambridge, UK.