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. 2017 Sep 12;8:1693. doi: 10.3389/fmicb.2017.01693

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Copyright © 2017 Amitai, Mesin, Victora, Kardar and Chakraborty.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fitness growth during the competitive phase. (A) Affinity distribution of a GC cell population at different days of the competitive phase. Affinity gradually increases as a traveling wave phenomena. The simulation was performed with D = 0.005. (B) Mean affinity as a function of time for the most dominant clone. Similar parameters were used as in Figures 2C–E. (C) Scatter plot of the number of clones in a GC vs. the affinity of the most dominant clone. (D) The ratio of the mean affinity of a GC population and its standard deviation.