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. 2017 Sep 11;8:630. doi: 10.3389/fphar.2017.00630

FIGURE 6.

FIGURE 6

The effects of KP extract on suppressing growth and survival signal transduction pathways. (A) Immunofluorescence of pERK1/2 in HeLa cells treated with KP extract. (B) Western blot showing immunoreactive bands of pPI3K, pAKT, pERK1/2, pElk1, and β-actin of HeLa cells stimulated with 100 ng/mL EGF and treated with different concentrations of KP extract. (C) Quantitative analysis of phosphorylation status of PI3K, AKT, ERK1/2, and Elk1 of HeLa cells treated with 100 ng/mL EGF and different concentrations of KP extract. Beta actin was used as an internal control and for normalization. Data are representative of three independent replicates and are expressed as mean ± SD. p < 0.05 compared with untreated cells.