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. 2017 Sep 12;8:1130. doi: 10.3389/fimmu.2017.01130

Figure 5.

Figure 5

T cell receptor (TCR) Vα2.3+ cells in Löfgren’s syndrome (LS) constitute a functionally heterogeneous population. t-stochastic neighborhood embedding (t-SNE) plots filtered for expression of Vα2.3 (A), CXCR3 (B), CCR4 (C), CCR6 (D), HLA-DR (E), CD11c (F), CD31 (G), and CTLA-4 (H) in LS bronchoalveolar lavage fluid cells. The main Vα2.3+ cluster is highlighted in red. Citrus comparison of Vα2.3+Vβ22− (I) and Vα2.3+Vβ22+ (J) clusters (24987 and 24983, respectively) reveals distribution of effector (e.g., CD127, CD28) and regulatory markers (e.g., PD-1, ICOS) to vary with TCR expression.