Table 4. Recurrent mutations in BRCA1/2 detected in 940 probands with personal and/or family history of breast/ovary cancer.

MUTATION	UNRELATED PROBANDS (% of the total probands)	REPORTED ORIGIN
BRCA1
c.211A>G (p.Arg71Gly)	11 (1.17)	Spanish
c.181T>G (p.Cys61Gly)	6 (0.64)	Italian
BRCA2
c.2808_2811delACAA (p.Lys936_Gln937LysGlnfs)	6 (0.64)	French
c.6037A>T (p.Lys2013*)	4 (0.42)	Portuguese / German
Total recurrents	32 (3.4)	-
Total recurrents / total mutated (179) = 17.8%	-	-

Note: The mutation in BRCA1: c.4964_4982del19 (p.Ser1655Tyrfs) is to be added in the recurrent mutations panel as it was found five times, including three recent patients (study in progress, see text).