Table 5. Multivariate Cox proportional hazards regression for disease-free survival (DFS) and cancer-specific survival (CSS) in patients with laryngeal squamous cell cancer (LSCC).
| DFS | P | CSS | P | |
|---|---|---|---|---|
| Characteristics | HR (95% CI) | HR (95% CI) | ||
| Tumor stage | <0.001 | <0.001 | ||
| T1-T2 | 1.000 | 1.000 | ||
| T3-T4 | 1.982 (1.538-2.553) | 2.236 (1.664-3.004) | ||
| Lymph node stage | <0.001 | 0.003 | ||
| N0 | 1.000 | 1.000 | ||
| N+ | 1.970 (1.431-2.712) | 1.766 (1.210-2.577) | ||
| Lymphocytes (×109/L) | 0.004 | 0.001 | ||
| >2.10 | 1.000 | 1.000 | ||
| 1.60-2.10 | 1.289 (0.947-1.754) | 0.106 | 1.718 (1.182-2.498) | 0.005 |
| <1.60 | 1.656 (1.227-2.235) | 0.001 | 1.977 (1.365-2.863) | <0.001 |
| NLR | 0.037 | 0.106 | ||
| <1.62 | 1.000 | 1.000 | ||
| 1.62-2.4 | 1.104 (0.810-1.506) | 0.531 | 1.289 (0.899-1.849) | 0.167 |
| >2.40 | 1.432 (1.066-1.925) | 0.017 | 1.464 (1.029-2.084) | 0.034 |
| PLR | 0.111 | 0.064 | ||
| <81.62 | 1.000 | 1.000 | ||
| 81.62-111.00 | 1.146 (0.844-1.555) | 0.384 | 1.219 (0.854-1.740) | 0.276 |
| >111.00 | 1.360 (1.015-1.821) | 0.039 | 1.502 (1.065-2.118) | 0.020 |
| LMR | 0.025 | 0.022 | ||
| >4.80 | 1.000 | 1.000 | ||
| 3.50-4.80 | 1.017 (0.744-1.390) | 0.915 | 1.119 (0.772-1.622) | 0.553 |
| <3.50 | 1.407 (1.046-1.891) | 0.024 | 1.565 (1.101-2.227) | 0.013 |
Bold values represent that P were two-sided and P<0.05 was statistically significant.
Abbreviation: DFS, disease-free survival; CSS, cancer-specific disease HR: hazard ratio; CI, confidence interval; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio.