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Serum folate concentrations in healthy young Japanese women with differing MTHFR C677T genotypes (CC, n = 36; CT, n = 47; TT, n = 17) at baseline and before and after supplementation with 200 and 400 μg/day folic acid. a, b, c MTHFR genotypes with the same superscripts differ significantly; P < 0.05. Reproduced from Hiraoka et al. (2004) with permission.
