NADPH-coupled
GPx assay for compounds 10, SLC-0111, and 22. Reaction conditions: [NADPH]0 =
0.6 mM, [GSH]0 = 2.0 mM, [H2O2]0 = 5 mM, [GR] = 8 units/mL, [catalyst] = 0.2 mM in pH 7.4
phosphate buffer at room temperature. Reported are the mean ±
SD values of three separate experiments.