Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 18;3:17063. doi: 10.1038/cddiscovery.2017.63

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Lauric acid triggers rapid responses in breast and endometrial cancer cells. (a, b) Phosphorylation of EGFR, ERK1/2 and c-Jun in SkBr3 (a) and Ishikawa (b) cells treated with vehicle (−) and 100 μM LA, as indicated. (c, d) EGFR, ERK1/2 and c-Jun activation in SkBr3 (c) and Ishikawa (d) cells treated for 60 min with vehicle or 100 μM LA alone or in combination with 10 μM EGFR inhibitor AG1478 (AG), 10 μM MEK inhibitor PD98089 (PD), 1 μM JNK inhibitor SP 600125 (SP) and 10 μM ROCK inhibitor Y-27632 (Y). EGFR, ERK2 and c-Jun were used as loading controls for pEGFR, pERK1/2 and pc-Jun, respectively. Results shown are representative of at least two independent experiments.