Table 2.

Age-related decrease of cortical thickness.

Hemisphere	Region	x (mm)	y (mm)	z (mm)	Size (mm2)	p-Value
Left	Pars opercularis	−51	13.7	14.5	7,238.17	<0.001
Left	Superior frontal	−6.2	44.3	39.6	3,781.02	<0.001
Left	Precuneus	−8.7	−58.4	12.3	1,667.50	<0.001
Left	Postcentral	−7.7	−39.1	69.5	1,445.48	<0.001
Left	Cuneus	−3.8	−76.8	20.8	1,243.02	<0.001
Left	Fusiform	−35	−44.4	−14	791.85	<0.001
Left	Lateral orbitofrontal	−40	25.9	−13	757.29	0.001
Left	Inferior temporal	−51	−63.1	−3	621.06	0.00459
Left	Superior parietal	−26	−40	51.6	538.25	0.01077
Left	Rostral middle frontal	−39	47.4	8.2	516.72	0.01395
Right	Lateral orbitofrontal	29.4	24.3	−0.7	9,523.02	<0.001
Right	Superior frontal	7.6	4.4	54.6	2,498.33	<0.001
Right	Inferior parietal	43.3	−64.3	6.3	1,721.20	<0.001
Right	Superior parietal	18.2	−86.3	20.3	1,391.03	<0.001
Right	Postcentral	17.6	−36	67.7	617.76	0.0038
Right	Superior parietal	11.5	−81.8	33.4	600.39	0.00459
Right	Precuneus	11.8	−46.8	65.9	518.42	0.01296
Right	Superior parietal	30.4	−55.6	42	510.94	0.01355

The table lists all clusters in which cortical thickness significantly decreases with age. Size and p-value of each cluster are noted. The anatomical location of the vertex with highest significance and its x, y, and z coordinates in Montreal Neurological Institute 305 space are given.