Figure 3. Assessment of human neutrophil viability in response to kinase inhibitor treatment.

Human peripheral blood neutrophils from three healthy donors were primed with G-CSF or GM-CSF for 1 hour before addition of selected kinase inhibitors (as shown) or DMSO (control) at concentrations as indicated. Neutrophil viability was assessed after 18 hours of treatment, by propidium iodide exclusion measured by flow cytometry. Mean ± SEM shown.