Figure 5. Inhibitory effect of sialyllactose on VEGF-induced in vivo neovascularization.

Matrigels were mixed with the indicated concentrations of sialyllactose in the presence of VEGF (50 ng/mL). The mixed matrigels were inoculated into the abdomen of mice. After a week, the matrigels were separated from euthanized mice. (A) Representative photographs and (B) histological images are shown. (C) Endothelial cells in paraffin section of Matrigel plug were counted. *** p<0.001 compared to the control (1^st lane), ### p<0.001 compared to the positive control (2^nd lane).