Table 3. Differentially expressed miRNAs in invasive cells or their exosomes analyzed by microarray.

MiRNAs only deregulated in invasive UBC cells
MiRNA	P-value	Q-value	FC	Expression
hsa-miR-205-3p	0.01	0.03	0.03	down
hsa-miR-148a-3p	0.02	0.04	0.05	down
hsa-miR-203a-5p	0.01	< 0.001	0.08	down
hsa-miR-224-3p	0.04	0.04	0.09	down
hsa-miR-335-3p	0.04	0.15	0.10	down
hsa-miR-183-5p	0.01	0.01	0.11	down
hsa-miR-141-5p	0.01	< 0.001	0.11	down
hsa-miR-200a-5p	0.01	0.02	0.15	down
hsa-miR-301b-3p	0.01	0.001	0.15	down
hsa-miR-340-5p	0.02	0.04	0.15	down
hsa-miR-149-5p	0.01	< 0.001	0.17	down
hsa-miR-182-5p	0.01	0.04	0.18	down
hsa-miR-96-5p	0.01	0.04	0.17	down
hsa-miR-194-5p	0.02	0.04	0.18	down
hsa-miR-215-5p	0.04	0.04	0.20	down
hsa-miR-192-5p	0.02	0.05	0.21	down
hsa-miR-301a-3p	0.01	0.04	0.22	down
hsa-miR-34c-5p	0.04	0.13	0.24	down
hsa-miR-200b-5p	0.01	0.03	0.24	down
hsa-miR-33a-5p	0.01	0.04	0.26	down
hsa-miR-148b-3p	0.04	0.13	0.29	down
hsa-miR-378a-5p	0.01	0.04	0.29	down
hsa-miR-22-5p	0.02	0.10	3.49	up
hsa-miR-30a-5p	0.04	0.16	3.42	up
hsa-miR-22-3p	0.01	0.04	3.90	up
hsa-miR-135a-3p	0.02	0.14	4.40	up
hsa-miR-140-3p	0.01	0.02	5.25	up
hsa-miR-630-3p	0.02	0.07	5.61	up
MiRNAs only deregulated in exosomes secreted by invasive UBC cells
MiRNA	P-value	Q-value	FC	Expression
hsa-miR-27b-3p	0.04	0.99	0.27	down
hsa-miR-503-5p	0.04	0.99	2.87	up
hsa-miR-513b-5p	0.02	0.99	2.87	up
hsa-miR-145-5p	0.04	0.99	3.38	up
hsa-miR-3158-3p	0.02	0.99	3.39	up
hsa-miR-30a-3p	0.02	0.99	4.27	up

Invasive cells n = 6; non-invasive cells n = 4; biological replicates per cell line n = 2; P-value was determined using Mann–Whitney U test. Q-value was determined using Student's t test. P < 0.05; FC > 1.5; σ = 0.2 (FC = Fold Change).