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. 2017 Apr 24;8(35):58625–58641. doi: 10.18632/oncotarget.17382

Figure 1. Elevated BMPR2 expression is predictive of poor outcome in osteosarcoma patients.

Figure 1

(A) (Left) Kaplan-Meier metastasis-free survival curve for osteosarcoma patients in the GSE33383 database showing the impact of BMPR2 expression on outcome. (Right) Kaplan-Meier curves of overall survival for osteosarcoma patients in the GSE33383 database based on BMPR2 expression. (B) Western blotting showing that BMPR2 is expressed in osteosarcoma but not in normal bone tissues. The data on BMPR2 expression levels in osteosarcoma and normal bone tissues are presented as the mean ± S.D. (n=12). **P<0.01. (C) IHC staining for BMPR2 expression in osteosarcoma samples and normal bone tissue. Representative images were photographed at ×400. (D) (Left) Kaplan-Meier curves showing the metastasis-free survival of 67 osteosarcoma patients. (Right) Kaplan-Meier curves showing the impact of BMPR2 expression on overall survival for 67 osteosarcoma patients.