Figure 6. HOTAIR promotes the nuclear translocation of YAP1.
(A) HOTAIR knockdown inhibited YAP1 translocation. (B) HOTAIR overexpression significantly upregulated YAP1 expression and nuclear translocation. (C and D) SAV1 overexpression or EZH2 inhibitor (GSK503) suppressed YAP1 expression and nuclear translocation.