Table 2. Univariable and multivariable Cox regression analyses in each data set.
Variables | Univariable modela | Multivariable model | ||||
---|---|---|---|---|---|---|
HR | 95% CI of HR | P value | HR | 95% CI of HR | P value | |
Training set (n=220) | ||||||
Five-lncRNA risk score | 1.151 | 1.104-1.200 | <0.001 | 1.131 | 1.086-1.178 | <0.001 |
Age | 1.019 | 1.001-1.038 | 0.034 | 1.021 | 1.002-1.040 | 0.032 |
Gender | 1.016 | 0.654-1.580 | 0.943 | 0.780 | 0.491-1.238 | 0.291 |
AJCC stage | 3.675 | 2.323-5.816 | <0.001 | 3.390 | 2.104-5.449 | <0.001 |
Tumor grade | 2.820 | 1.718-4.630 | <0.001 | 1.752 | 0.999-3.071 | 0.050 |
Testing set (n=220) | ||||||
Five-lncRNA risk score | 1.057 | 1.011-1.104 | 0.014 | 1.055 | 1.014-1.098 | <0.001 |
Age | 1.040 | 1.017-1.063 | <0.001 | 1.041 | 1.017-1.066 | <0.001 |
Gender | 0.904 | 0.540-1.513 | 0.701 | 1.339 | 0.777-2.309 | 0.294 |
AJCC stage | 5.121 | 2.908-9.016 | <0.001 | 4.440 | 2.419-8.150 | <0.001 |
Tumor grade | 2.374 | 1.326-4.252 | 0.004 | 1.542 | 0.834-2.852 | 0.167 |
Entire set (n=440) | ||||||
Five-lncRNA risk score | 1.106 | 1.073-1.139 | <0.001 | 1.093 | 1.063-1.125 | <0.001 |
Age | 1.029 | 1.015-1.044 | <0.001 | 1.030 | 1.015-1.045 | <0.001 |
Gender | 0.958 | 0.685-1.339 | 0.802 | 0.964 | 0.678-1.371 | 0.179 |
AJCC stage | 4.217 | 2.956-6.015 | <0.001 | 3.269 | 2.232-4.787 | <0.001 |
Tumor grade | 2.582 | 1.770-3.767 | <0.001 | 1.675 | 1.121-2.501 | 0.012 |
a In both univariable and multivariable Cox regression analyses, risk score, age, gender, AJCC stage and Tumor grade were evaluated as continuous variables. P<0.05 was considered statistically significant in all analyses.