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. 2017 Aug 1;8(35):58985–58999. doi: 10.18632/oncotarget.19775

Figure 4. Diffusion tensor tractography (DTT) figures, H.E staining of rat spinal cord tissue and BBB locomotor function score.

Figure 4

(A) The DTT. In Injury group, the spinal cord fibers continuity were interrupted from the 1st day to 28th day, and end fibers arranged disorderly, colors were uneven; In Repaired group, the nerve fibers from the 1st day to 28th day, some fibers connected to the other end. The color was almost consistent, but the arrangement of neurofibra was still disorder. (B) a. In Normal group, visible normal spinal structure; b. In Injury 1d group, spinal cord was completely broken; c. In Repaired 28 d group, continuous spinal nerve fibers appeared in SCI site. (C) BBB locomotor function score. BBB scores increased gradually from 2～8 weeks in BMSCs repaired group. After transplant 8 weeks, BBB scores (score > 8)were significantly higher than Injury group(score < 4), **P < 0.01.