Table 3. Multivariate analysis of PFS in patients with lung adenocarcinoma treated with EGFR-TKI.

Variables		HR	95% CI	p value
Smoking Status	Never-smoker vs. Ever-smoker (Ref)	0.488	0.236–1.007	0.052
N	0 and 1 vs. 2 and 3 (Ref)	1.488	0.825–2.683	0.187
PHLPP1 expression	High expression vs. Low expression (Ref)	0.232	0.123–0.438	0.000
pAKT (S473) expression	High expression vs. Low expression (Ref)	1.439	0.634–3.266	0.384
pERK 1/2 expression	High expression vs. Low expression (Ref)	0.666	0.339–1.310	0.239