Table 2. Univariate and multivariate analyses of the relationships between hematological parameters and the significant fibrosis in the entire patients.
| Variables | Significant fibrosis (F2–F4) | |||
|---|---|---|---|---|
| Univariate | P-value | Multivariate | P-value | |
| Age | 1.047 (1.022, 1.073) | <0.001 | ||
| Neutrophils | 0.795 (0.651, 0.970) | 0.024 | ||
| Lymphocytes | 0.708 (0.468, 1.072) | 0.103 | ||
| Monocytes | 0.421 (0.056, 3.182) | 0.402 | ||
| RBC | 0.559 (0.339, 0.909) | 0.019 | ||
| Hb | 0.999 (0.986, 1.012) | 0.832 | ||
| RDW-CV | 1.014 (0.851, 1.208) | 0.877 | ||
| RDW-SD | 1.135 (1.063, 1.212) | <0.001 | 1.125 (1.048, 1.207) | 0.001 |
| PLT | 0.989 (0.985, 0.994) | <0.001 | 0.990 (0.985, 0.995) | <0.001 |
| TBIL | 1.034 (1.001, 1.069) | 0.045 | ||
| Albumin | 0.965 (0.908, 1.025) | 0.245 | ||
| Globulin | 1.097 (1.038, 1.116) | 0.001 | 1.084 (1.018, 1.155) | 0.012 |
| ALT | 1.001 (0.999, 1.004) | 0.303 | ||
| AST | 1.005 (0.999, 1.012) | 0.119 | ||
| ALP | 1.02 (1.008, 1.032) | 0.001 | 1.015 (1.002, 1.028) | 0.021 |
| GGT | 1.005 (1.000, 1.009) | 0.04 | ||
| LDH | 1.003 (0.997, 1.009) | 0.379 | ||
| CHE | 1.000 (1.000, 1.000) | 0.008 | ||
| INR | 14.857 (1.554, 142.066) | 0.019 | ||
| TT | 1.271 (1.055, 1.531) | 0.012 | ||
RBC: red blood cell; Hb: hemoglobin; RDW-CV: the coefficient of variation of the red blood cell distribution width; RDW-SD: the standard deviation of the red blood cell distribution width; PLT: platelets; TBIL: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; GGT: gamma-glutamyl transpeptidase; LDH: lactic dehydrogenase; CHE: cholinesterase; TT: thrombin time; INR: international normalized ratio.