Table 4. Diagnostic performance of the diagnostic panel in the discovery and validation cohorts.

	Diagnostic group	Real group		Accuracy rate	Sensitivity (95% CI)	Specificity (95% CI)	AUC (95% CI)	P-value
		CRC patients	Controls
Discovery cohort	CRC patients	96	5	95.5%	96.0%	95.0%	0.982	<0.001
(n=200)	Controls	4	95		(92.2%-99.8%)	(90.7%-99.3%)	(0.965-0.998)
Validation cohort	CRC patients	87	11	91.8%	95.6%	87.9%	0.932	<0.001
(n=182)	Controls	4	80		(91.6%-99.6%)	(81.5%-94.3%)	(0.892-0.973)