Table 4. SH2B3 haplotype frequencies and CAD risk association in the women group.
Gene | SNP | Haplotype | Frequency (%) | OR 95%CI | p | |
---|---|---|---|---|---|---|
Cases | Controls | |||||
SH2B3 | rs7309325|rs2078863|rs7296313 | TCC | 0.545 | 0.492 | 1 | --- |
TTC | 0.361 | 0.451 | 0.59 (0.40 - 0.86) | 0.007* | ||
GTT | 0.082 | 0.085 | 0.79 (0.41 - 1.53) | 0.490 | ||
--- | --- | --- | 0.97 (0.18 - 5.15) | 0.970 |
OR = odds ratio; 95 % CI = 95 % confidence interval
p values were calculated using two-sided Chi-square test without adjustment for age
*p < 0.05 indicates statistical significance