Table 6. Lipid levels measured for SNP genotypes in the men and women populations.
SNP | TG (mmol/L) | p | TC (mmol/L) | p | HDL (mmol/L) | p | LDL (mmol/L) | p | APOA1/APOB | p |
---|---|---|---|---|---|---|---|---|---|---|
Men population (n = 291) | ||||||||||
rs3742003 | ||||||||||
A/A (n = 221) | 1.8687 ± 1.798 | 0.211 | 3.929 ± 1.14474 | 0.455 | 1.0817 ± 0.247 | 0.055 | 1.8005 ± 0.682 | 0.049* | 1.438 ± 0.744 | 0.726 |
G/A (n = 64) | 1.5745 ± 0.962 | 4.0567 ± 1.321 | 1.1503 ± 0.257 | 2.0514 ± 1.364 | 1.473 ± 0.609 | |||||
rs12580300 | ||||||||||
G/G (n = 92) | 1.6597 ± 1.1596 | 0.587 | 3.99 ± 1.193 | 0.610 | 1.108 ± 0.264 | 0.768 | 2.0148 ± 1.163 | 0.107 | 1.487 ± 0.988 | 0.463 |
A/A (n = 41) | 1.8168 ± 1.3119 | 4.0898 ± 1.038 | 1.1102 ± 0.273 | 1.8382 ± 0.597 | 1.327 ± 0.480 | |||||
G/A (n = 139) | 1.8881 ± 1.9825 | 3.8954 ± 1.2286 | 1.0868 ± 0.234 | 1.7623 ± 0.742 | 1.457 ± 0.542 | |||||
rs7309325 | ||||||||||
T/T (n = 213) | 1.8592 ± 1.7928 | 0.271 | 3.9294 ± 1.1429 | 0.451 | 1.0824 ± 0.2458 | 0.062 | 1.8017 ± 0.6819 | 0.048* | 1.437 ± 0.7411 | 0.709 |
G/T (n = 62) | 1.5976 ± 0.9665 | 4.0595 ± 1.3322 | 1.1498 ± 0.2611 | 2.0555 ± 1.3812 | 1.476 ± 0.6161 | |||||
rs7296313 | ||||||||||
C/C (n = 215) | 1.8807 ± 1.7968 | 0.125 | 3.9401 ± 1.1415 | 0.628 | 1.0864 ± 0.2548 | 0.158 | 1.8005 ± 0.6803 | 0.040* | 1.442 ± 0.7444 | 0.864 |
T/C (n = 60) | 1.5122 ± 0.8676 | 4.0247 ± 1.3458 | 1.138 ± 0.2319 | 2.0682 ± 1.400 | 1.46 ± 0.0772 | |||||
rs11879293 | ||||||||||
G/G (n = 172) | 1.933 ± 1.9368 | 0.224 | 3.8893 ± 1.0763 | 0.140 | 1.0934 ± 0.2457 | 0.324 | 1.7395 ± 0.6508 | 0.013* | 1.485 ± 0.7881 | 0.511 |
A/A (n = 13) | 1.6231 ± 0.9815 | 3.6023 ± 1.2987 | 1.01 ± 0.1292 | 1.9146 ± 0.7138 | 1.369 ± 0.5040 | |||||
G/A (n = 90) | 1.5721 ± 0.9515 | 4.1438 ± 1.3499 | 1.1184 ± 0.2708 | 2.079 ± 1.2209 | 1.383 ± 0.5787 | |||||
rs2072382 | ||||||||||
C/C (n = 119) | 1.745 ± 1.1847 | 0.573 | 3.9791 ± 1.2366 | 0.081 | 1.0771 ± 0.2341 | 0.257 | 1.8449 ± 0.8019 | 0.081 | 1.457 ± 0.6025 | 0.021* |
T/C (n = 122) | 1.9077 ± 1.9746 | 4.0543 ± 1.1807 | 1.1254 ± 0.2679 | 1.9537 ± 1.0251 | 1.354 ± 0.5 | |||||
T/T (n = 34) | 1.6082 ± 1.7521 | 3.5421 ± 0.9466 | 1.0697 ± 0.2378 | 1.5679 ± 0.5779 | 1.735 ± 1.3715 | |||||
Women population (n = 165) | ||||||||||
rs3742003 | ||||||||||
A/A (n = 127) | 1.6872 ± 0.7916 | 0.069 | 4.3562 ± 1.0572 | 0.304 | 1.2002 ± 0.2547 | 0.550 | 2.0403 ± 0.6762 | 0.085 | 1.405 ± 0.5733 | 0.036* |
G/A (n = 27) | 2.3096 ± 2.5019 | 4.153 ± 1.0764 | 1.1448 ± 0.3397 | 1.8841 ± 0.8282 | 1.785 ± 1.1370 | |||||
rs12580300 | ||||||||||
G/G (n = 62) | 1.9269 ± 1.7576 | 0.574 | 4.2015 ± 0.8815 | 0.464 | 1.1535 ± 0.2472 | 0.080 | 1.9276 ± 0.6519 | 0.368 | 1.434 ± 0.6677 | 0.285 |
A/A (n = 19) | 1.6637 ± 0.7636 | 4.3642 ± 1.2542 | 1.1268 ± 0.2492 | 2.1495 ± 0.7979 | 1.274 ± 0.5184 | |||||
G/A (n = 73) | 1.72 ± 0.8241 | 4.4273 ± 1.1479 | 1.2365 ± 0.2505 | 2.0682 ± 0.7359 | 1.551 ± 0.7881 | |||||
rs7309325 | ||||||||||
T/T (n = 127) | 1.6842 ± 0.7911 | 0.060 | 4.3565 ± 1.0572 | 0.305 | 1.2004 ± 0.2546 | 0.560 | 2.0382 ± 0.6769 | 0.094 | 1.408 ± 0.5727 | 0.036* |
G/T (n = 26) | 2.3358 ± 2.5476 | 4.1492 ± 1.0976 | 1.145 ± 0.2445 | 1.8919 ± 0.8436 | 1.796 ± 1.1581 | |||||
rs7296313 | ||||||||||
C/C (n = 127) | 1.694 ± 0.7912 | 0.097 | 4.3457 ± 1.0468 | 0.373 | 1.1967 ± 0.2546 | 0.753 | 2.032 ± 0.6697 | 0.113 | 1.402 ± 0.511 | 0.029* |
T/C (n = 27) | 2.2774 ± 2.5105 | 4.2022 ± 1.1328 | 1.1611 ± 0.2437 | 1.9233 ± 0.8599 | 1.796 ± 0.218 | |||||
rs11879293 | ||||||||||
G/G (n = 83) | 1.8205 ± 1.5942 | 0.929 | 4.1941 ± 0.9307 | 0.221 | 1.1711 ± 0.2454 | 0.550 | 1.9389 ± 0.6324 | 0.051 | 1.473 ± 0.6894 | 0.323 |
A/A (n = 11) | 1.6664 ± 0.8972 | 4.3755 ± 1.1683 | 1.2436 ± 0.3385 | 1.75 ± 0.6879 | 1.764 ± 1.1986 | |||||
G/A (n = 61) | 1.7857 ± 0.7488 | 4.5048 ± 1.1942 | 1.2057 ± 0.2444 | 2.1839 ± 0.7899 | 1.411 ± 0.6327 | |||||
rs2072382 | ||||||||||
C/C (n = 74) | 1.9289 ± 1.5378 | 0.358 | 4.3726 ± 0.9984 | 0.892 | 1.1814 ± 0.2459 | 0.303 | 1.9684 ± 0.6406 | 0.609 | 1.432 ± 0.6319 | 0.803 |
T/C (n = 70) | 1.7254 ± 1.0477 | 4.2901 ± 1.1109 | 1.2163 ± 0.2589 | 2.0529 ± 0.7795 | 1.496 ± 0.6449 | |||||
T/T (n = 13) | 1.4443 ± 0.4935 | 4.2929 ± 1.2073 | 1.1057 ± 0.2394 | 2.1507 ± 0.7514 | 1.543 ± 1.2924 |
Triglyceride = TG; Total Cholesterol = TC; Apolipoprotein A1/ Apolipoprotein B = APOA1/APOB;
High-density lipoprotein = HDL; Low-density lipoprotein = LDL
p values were calculated using t test
*p < 0.05 indicates statistical significance