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. 2017 Jul 31;8(35):59397–59407. doi: 10.18632/oncotarget.19720

Table 6. Lipid levels measured for SNP genotypes in the men and women populations.

SNP TG (mmol/L) p TC (mmol/L) p HDL (mmol/L) p LDL (mmol/L) p APOA1/APOB p
Men population (n = 291)
rs3742003
A/A (n = 221) 1.8687 ± 1.798 0.211 3.929 ± 1.14474 0.455 1.0817 ± 0.247 0.055 1.8005 ± 0.682 0.049* 1.438 ± 0.744 0.726
G/A (n = 64) 1.5745 ± 0.962 4.0567 ± 1.321 1.1503 ± 0.257 2.0514 ± 1.364 1.473 ± 0.609
rs12580300
G/G (n = 92) 1.6597 ± 1.1596 0.587 3.99 ± 1.193 0.610 1.108 ± 0.264 0.768 2.0148 ± 1.163 0.107 1.487 ± 0.988 0.463
A/A (n = 41) 1.8168 ± 1.3119 4.0898 ± 1.038 1.1102 ± 0.273 1.8382 ± 0.597 1.327 ± 0.480
G/A (n = 139) 1.8881 ± 1.9825 3.8954 ± 1.2286 1.0868 ± 0.234 1.7623 ± 0.742 1.457 ± 0.542
rs7309325
T/T (n = 213) 1.8592 ± 1.7928 0.271 3.9294 ± 1.1429 0.451 1.0824 ± 0.2458 0.062 1.8017 ± 0.6819 0.048* 1.437 ± 0.7411 0.709
G/T (n = 62) 1.5976 ± 0.9665 4.0595 ± 1.3322 1.1498 ± 0.2611 2.0555 ± 1.3812 1.476 ± 0.6161
rs7296313
C/C (n = 215) 1.8807 ± 1.7968 0.125 3.9401 ± 1.1415 0.628 1.0864 ± 0.2548 0.158 1.8005 ± 0.6803 0.040* 1.442 ± 0.7444 0.864
T/C (n = 60) 1.5122 ± 0.8676 4.0247 ± 1.3458 1.138 ± 0.2319 2.0682 ± 1.400 1.46 ± 0.0772
rs11879293
G/G (n = 172) 1.933 ± 1.9368 0.224 3.8893 ± 1.0763 0.140 1.0934 ± 0.2457 0.324 1.7395 ± 0.6508 0.013* 1.485 ± 0.7881 0.511
A/A (n = 13) 1.6231 ± 0.9815 3.6023 ± 1.2987 1.01 ± 0.1292 1.9146 ± 0.7138 1.369 ± 0.5040
G/A (n = 90) 1.5721 ± 0.9515 4.1438 ± 1.3499 1.1184 ± 0.2708 2.079 ± 1.2209 1.383 ± 0.5787
rs2072382
C/C (n = 119) 1.745 ± 1.1847 0.573 3.9791 ± 1.2366 0.081 1.0771 ± 0.2341 0.257 1.8449 ± 0.8019 0.081 1.457 ± 0.6025 0.021*
T/C (n = 122) 1.9077 ± 1.9746 4.0543 ± 1.1807 1.1254 ± 0.2679 1.9537 ± 1.0251 1.354 ± 0.5
T/T (n = 34) 1.6082 ± 1.7521 3.5421 ± 0.9466 1.0697 ± 0.2378 1.5679 ± 0.5779 1.735 ± 1.3715
Women population (n = 165)
rs3742003
A/A (n = 127) 1.6872 ± 0.7916 0.069 4.3562 ± 1.0572 0.304 1.2002 ± 0.2547 0.550 2.0403 ± 0.6762 0.085 1.405 ± 0.5733 0.036*
G/A (n = 27) 2.3096 ± 2.5019 4.153 ± 1.0764 1.1448 ± 0.3397 1.8841 ± 0.8282 1.785 ± 1.1370
rs12580300
G/G (n = 62) 1.9269 ± 1.7576 0.574 4.2015 ± 0.8815 0.464 1.1535 ± 0.2472 0.080 1.9276 ± 0.6519 0.368 1.434 ± 0.6677 0.285
A/A (n = 19) 1.6637 ± 0.7636 4.3642 ± 1.2542 1.1268 ± 0.2492 2.1495 ± 0.7979 1.274 ± 0.5184
G/A (n = 73) 1.72 ± 0.8241 4.4273 ± 1.1479 1.2365 ± 0.2505 2.0682 ± 0.7359 1.551 ± 0.7881
rs7309325
T/T (n = 127) 1.6842 ± 0.7911 0.060 4.3565 ± 1.0572 0.305 1.2004 ± 0.2546 0.560 2.0382 ± 0.6769 0.094 1.408 ± 0.5727 0.036*
G/T (n = 26) 2.3358 ± 2.5476 4.1492 ± 1.0976 1.145 ± 0.2445 1.8919 ± 0.8436 1.796 ± 1.1581
rs7296313
C/C (n = 127) 1.694 ± 0.7912 0.097 4.3457 ± 1.0468 0.373 1.1967 ± 0.2546 0.753 2.032 ± 0.6697 0.113 1.402 ± 0.511 0.029*
T/C (n = 27) 2.2774 ± 2.5105 4.2022 ± 1.1328 1.1611 ± 0.2437 1.9233 ± 0.8599 1.796 ± 0.218
rs11879293
G/G (n = 83) 1.8205 ± 1.5942 0.929 4.1941 ± 0.9307 0.221 1.1711 ± 0.2454 0.550 1.9389 ± 0.6324 0.051 1.473 ± 0.6894 0.323
A/A (n = 11) 1.6664 ± 0.8972 4.3755 ± 1.1683 1.2436 ± 0.3385 1.75 ± 0.6879 1.764 ± 1.1986
G/A (n = 61) 1.7857 ± 0.7488 4.5048 ± 1.1942 1.2057 ± 0.2444 2.1839 ± 0.7899 1.411 ± 0.6327
rs2072382
C/C (n = 74) 1.9289 ± 1.5378 0.358 4.3726 ± 0.9984 0.892 1.1814 ± 0.2459 0.303 1.9684 ± 0.6406 0.609 1.432 ± 0.6319 0.803
T/C (n = 70) 1.7254 ± 1.0477 4.2901 ± 1.1109 1.2163 ± 0.2589 2.0529 ± 0.7795 1.496 ± 0.6449
T/T (n = 13) 1.4443 ± 0.4935 4.2929 ± 1.2073 1.1057 ± 0.2394 2.1507 ± 0.7514 1.543 ± 1.2924

Triglyceride = TG; Total Cholesterol = TC; Apolipoprotein A1/ Apolipoprotein B = APOA1/APOB;

High-density lipoprotein = HDL; Low-density lipoprotein = LDL

p values were calculated using t test

*p < 0.05 indicates statistical significance