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. 2017 May 10;8(35):59492–59499. doi: 10.18632/oncotarget.17752

Table 2. Methodological quality of the involved 39 studies according to the QUADAS criteria.

Yes (%) No (%) Unclear (%)
Patient spectrum 24 (61.54) 8 (20.51) 7 (17.95)
Selection criteria 25 (64.10) 10(25.64) 4(10.26)
Reference standard 39 (100)
Disease progression bias 39 (100)
Partial verification bias 39 (100)
Differential verification bias 39 (100)
Incorporation bias 39 (100)
Text details 39 (100)
Reference standard details 39 (100)
Text review details 18 (46.15) 8 (20.51) 13 (33.33)
Diagnostic review bias 18 (46.15) 9 (23.08) 12 (30.77)
Clinical review bias 38 (97.44) 1 (2.56)
Uninterpretable results 38 (97.44) 1 (2.56)
Withdrawals explained 38 (97.44) 1 (2.56)