Table 1.
Basic descriptive statistics for all simulations and neuronal recordings.
| Simulations | |
| Classification training data | |
| Number of simulations | 60 |
| Connectivity degree3 | 20.1% ± 5.0% |
| Propagation probability3 | 3.9% ± 0.9% |
| Number of cells per simulation3 | 43 ± 0 |
| Classification test data | |
| Number of simulations | 840 |
| Connectivity degree | 5–80% |
| Propagation probability | 5–80% |
| Number of cells per simulation | 30–101 |
| Recordings | |
| Control group, 2 days incubation | |
| Treatment | 2 days incubation with according volume of water |
| Number of recordings1 | 11 (12) |
| Culture age at recording2 | DIV 12–17 |
| Connectivity degree3 | 21.1% ± 7.0% |
| Propagation probability3 | 19.6% ± 10.1% |
| Number of cells per recording3 | 34.9 ± 17.4 |
| Control group, 6 days incubation | |
| Treatment | 6 days incubation with according volume of water |
| Number of recordings1 | 18 (18) |
| Culture age at recording2 | DIV 13–15 |
| Connectivity degree3 | 19.6% ± 12.3% |
| Propagation probability3 | 14.5% ± 5.2% |
| Number of cells per recording3 | 44.5 ± 13.2 |
| Silencing group, 2 days incubation | |
| Treatment | 2 days incubation with 500 nM TTX |
| Number of recordings1 | 16 (22) |
| Culture age at recording2 | DIV 12–17 |
| Connectivity degree3 | 37.2% ± 27.1% |
| Propagation probability3 | 45.9% ± 21.2% |
| Number of cells per recording3 | 40.6 ± 21.5 |
| Silencing group, 2 days incubation | |
| Treatment | 2 days incubation with 1 µM TTX |
| Number of recordings1 | 13 (15) |
| Culture age at recording2 | DIV (13–15) |
| Connectivity degree3 | 45.1% ± 20.4% |
| Propagation probability3 | 37.1% ± 20.5% |
| Number of cells per recording3 | 43.1 ± 18.6 |
| Silencing group, 6 days incubation | |
| Treatment | 6 days incubation with 1 µM TTX |
| Number of recordings1 | 17 (23) |
| Culture age at recording2 | DIV 13–15 |
| Connectivity degree3 | 24.2% ± 15.7% |
| Propagation probability3 | 34.5% ± 12.1% |
| Number of cells per recording3 | 49.2 ± 28.5 |
1The numbers of recordings are shown as analyzed recordings (total number of conducted experiments). Recordings with less than 30 active neurons were excluded from the analysis. 2DIV = day in vitro. 3Connectivity degree, propagation probability and number of cells per simulation/ recording are shown as mean ± standard deviation.