Table 1. Functional comparison of genes involved in hypomyelination and PLMD.

Gene name	Gene functions
GJC2	Peripheral myelination
SLC16A2	Development of the central nervous system
DARS and RARS	Aminoacylation and multi-tRNA synthetase complex structure
AIMP1	Multi-tRNA synthetase complex structure
POLR3A, POLR3B and POLR1C	Polymerase subunit
HSPD1	Folding and assembly of proteins in the mitochondria
FAM126A	Beta-catenin signalling pathway
TUBB4A	Beta tubulin compartment
VPS11	Vesicle trafficking in the endosome/lysosome pathway
PYCR2	Proline biosynthesis