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. 2017 May 13;36(10):1811–1818. doi: 10.1007/s10096-017-2996-6

Table 3.

Associations of IL1B rs16944 (−511 C/T) and TNF rs1799964 (−1031 T/C) polymorphism with congenital CMV infection

Polymorphism SNP database ID number Genotype Children, n (%) Unadjusted analysis Adjusted analysis
Congenital CMV (n = 72) Healthy control (n = 398) OR (95% CI) P-value OR (95% CI) P-value a
IL1B rs16944 CC + CT 59 (81.9) 366 (92) 1 0.014 1 0.032
TT 13 (18.1) 32 (8) 2.52 (1.25–5.08) 2.32 (1.11–4.89)
TNF rs1799964 TT + CC 43 (59.7) 303 (76.1) 1 0.005 1 0.007
TC 29 (40.3) 95 (23.9) 2.15 (1.27–3.63) 2.17 (1.25–3.77)

a P-value calculated for regression model adjusted for mother’s CMV status and age at delivery