Table 3.
Polymorphism SNP database ID number | Genotype | Children, n (%) | Unadjusted analysis | Adjusted analysis | |||
---|---|---|---|---|---|---|---|
Congenital CMV (n = 72) | Healthy control (n = 398) | OR (95% CI) | P-value | OR (95% CI) | P-value a | ||
IL1B rs16944 | CC + CT | 59 (81.9) | 366 (92) | 1 | 0.014 | 1 | 0.032 |
TT | 13 (18.1) | 32 (8) | 2.52 (1.25–5.08) | 2.32 (1.11–4.89) | |||
TNF rs1799964 | TT + CC | 43 (59.7) | 303 (76.1) | 1 | 0.005 | 1 | 0.007 |
TC | 29 (40.3) | 95 (23.9) | 2.15 (1.27–3.63) | 2.17 (1.25–3.77) |
a P-value calculated for regression model adjusted for mother’s CMV status and age at delivery