Table 3.
Time to detection (TTD) and detection rates from BacT/ALERT® 3D and VIRTUO™ by bottle type and blood volume
| Bottle type | Blood volume (mL) | 3D | VIRTUO™ | TTD difference (3D - VIRTUO™) | |||
|---|---|---|---|---|---|---|---|
| # (+)/# | Detection rate (%) | # (+)/# | Detection rate (%) | Mean TTD difference (h) | 95% CI for mean TTD difference (h) | ||
| FA Plus | 0 | 227/239 | 95.0 | 233/233 | 100.0* | 3.62 | (3.37, 3.86) |
| 4** | 271/272 | 99.6 | 275/275 | 100.0 | 3.94 | (3.47, 4.41) | |
| 10 | 273/278 | 98.2 | 279/279 | 100.0* | 3.24 | (2.96, 3.51) | |
| Combined | 771/789 | 97.7 | 787/787 | 100.0* | 3.59 | (3.39, 3.80) | |
| FN Plus | 0 | 93/93 | 100.0 | 91/91 | 100.0 | 3.62 | (3.14, 4.10) |
| 4 | 117/121 | 96.7 | 122/122 | 100.0* | 3.78 | (3.27, 4.29) | |
| 10 | 110/115 | 95.7 | 114/114 | 100.0* | 4.28 | (3.93, 4.64) | |
| Combined | 320/329 | 97.3 | 327/327 | 100.0* | 3.90 | (3.64, 4.17) | |
| SA | 0 | 215/215 | 100.0 | 213/213 | 100.0 | 2.35 | (2.13, 2.56) |
| 4 | 276/276 | 100.0 | 279/279 | 100.0 | 3.47 | (3.33, 3.61) | |
| 10 | 270/270 | 100.0 | 276/276 | 100.0 | 3.38 | (3.14, 3.62) | |
| Combined | 761/761 | 100.0 | 768/768 | 100.0 | 3.14 | (3.02, 3.25) | |
| SN | 0 | 125/125 | 100.0 | 123/123 | 100.0 | 4.65 | (4.46, 4.84) |
| 4 | 124/124 | 100.0 | 116/117 | 99.1 | 4.02 | (3.76, 4.29) | |
| 10 | 119/120 | 99.2 | 119/120 | 99.2 | 2.20 | (1.58, 2.82) | |
| Combined | 368/369 | 99.7 | 358/360 | 99.4 | 3.65 | (3.42, 3.88) | |
| Overall | 2220/2248 | 98.8 | 2240/2242 | 99.9* | 3.48 | (3.38, 3.58) | |
*Significant difference between detection rates; Fisher’s exact test p-value <0.05; **represents PF Plus