Putative RNA binding domains in yeast ncRNA binding proteins (BP). Frequencies were calculated as the percentage of proteins that contain a certain domain in the yeast proteome/6000 (occurrence in the yeast proteome A,D), proteins that contain a domain in the ncRNA interactome/173 protein nodes (occurrence in yeast RPI B,D), or proteins that contain a domain/120 mRNA BP from Mitchell et al. (2013) (C). (D) Frequencies of the most represented protein domains in the yeast ncRNA binding proteins. (Note that in A, KH, DSRM, PUMILIO, C3H1, and S1 are barely visible, due to their frequencies being 0.1% or less, while in B, C3H1 and Pumilio are absent, and in C, C2H2 is absent.)