Table 1.
Classes of immunosuppressive drugs used in ocular inflammation.
| Classs | Generic name | Trade name |
|---|---|---|
| Antimetabolites | Azathioprine | Imuran |
| Methotrexate | Rheumatrex | |
| Mycophenolate mofetil | CellCept | |
| T-cell/calcineurin inhibitors | Cyclosporine | Sandimmune |
| Neoral | ||
| Gengraf | ||
| Tacrolimus | Prograf | |
| Voclosporina | Luveniqa | |
| Alkylating agents | Cyclophosphamide | Cytoxan |
| Chlorambucil | Leukeran | |
| Biologics | ||
| TNF inhibitors | Etanercept | Enbrel |
| Infliximab | REMICADE | |
| Adalimumab | Humira | |
| Lymphocyte inhibitors | Rituximab | RITUXAN |
| Abatacept | ORENCIA | |
| Interferons | Interferon alpha-2a | Roferon-A |
| IL-1 antagonist | Anakinra | Kineret |
| IL-2 antagonist | Daclizumab a | Zenapax a |
IL = interleukin; TNF = tumor necrosis factor.
a Not on the market.