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BAFF induces IgM and IgG production from memory, but not naive, B cells. Naive (A) and memory (B) B cells were cultured as described in Fig.1. IgM and IgG in culture supernatant from indicated conditions were measured by ELISA on day 5. Graphs are shown as mean concentration ± SEM. n = 8 for naive, n = 9 for memory B cells. One-way ANOVA compared with IL-2/IL-21–only condition. *p < 0.05, **p < 0.005, ***p < 0.001.
