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. 2017 Aug 1;292(37):15266–15276. doi: 10.1074/jbc.M117.787846

Figure 5.

Figure 5.

p38 activation is not sufficient to inhibit NMD. a, levels of MKK6, both total p38α and phosphorylated p38 and HSP27 in RPE1 cells expressing LacZ or constitutively active MKK6-CA for 7 days. b, comparison of the levels of total p38α and phosphorylated p38 in RPE1 cells overexpressing either LacZ or MKK6-CA for 7 days with that in RPE cells treated with either H2O or bleomycin (Bleo) for 24 h, followed by 96-h recovery. c, ratios of CBR:CBG bioluminescence signals in RPE1 reporter cells expressing either LacZ or MKK6-CA for 7 days. Data represent the mean ± S.D. of three independent experiments. NS, p > 0.05 (paired t test).